DEVELOPMENTAL BIOLOGY----BIOL 3160

                                                          SPRING TERM 2004

 

 

 

Instructor:            Dr. Rosalind (Roz) Herlands

Office:                   C-107 (ext 4402)

e-mail address:     rherlands@stockton.edu

URL for web page:          http://www.stockton.edu/~herlandr

Home phone;        965-3611

Office Hours;        Mon 11:30-12:30; Weds 2:10-3:25; Friday 11:30-12:30; or by

                                     appointment

 

Welcome to Developmental Biology!  This is an exciting field of biology that is helping us bring together ideas and experimental approaches from cell biology, genetics, immunology, physiology and anatomy to understand how animals and plants have evolved and how they develop from fertilized eggs to sexually mature adults to aging individuals.  This course will be primarily concerned with the development of animals, but we will also discuss some processes occurring in the embryonic development of flowering plants.  The course has three lecture sessions and a laboratory meeting (Tuesdays from 8:30-11:15 in F-005) each week; the lab exercises--all experimental--will involve investigations on developing animals and plants and will illustrate the lecture and reading concepts and topics.

 

On the following pages, I have outlined a tentative syllabus for the course, indicating the sequence of topics and readings as well as the dates of the exams.  I have also included the topics and dates for the lab exercises.

 

Pre-requisites:      a year of general biology, Chem II (or Organic Chem I), and Genetics

 

Readings:             We will be using Developmental Biology, 7th ed. by Scott Gilbert as the main text and will occasionally supplement it with journal articles and assigned readings on reserve in the Library.

 

Exams:                 There will be three essay exams (given on 2/20, 3/31, 5/5) which will cover the lecture and lab material and assigned readings; the exams will be of equal weight; expect frequent take-home quizzes.  There are NO make-ups on exams or quizzes.

 

Lab Reports:         You will be writing several lab reports based on the lab exercises.

 

Grading:               Your final course grade will be based on your three exams, quizzes, lab reports and participation in class.  Grades on your lab assignments will

                             make up 25% of your course grade.

 

                                                             COURSE SYLLABUS

 

Dates                                       Topics                                                  Readings in Textbook

Jan 21                  introduction to development                                  chapter 1

 

Jan 23                  developmental patterns                                          chapter 2

 

Jan 26                  cells & genes in development (review)                    chapters  5[107-111]

 

Jan 28                  fertilization                                                             chapter 7

 

Jan 30                        “                                                                              “

                               

Feb 2                    early development: cleavage and gastrulation        chapter 8

         

Feb 4                    early development in sea urchins                                 “

                  

Feb 6                    early development in snails and tunicates                     “

 

Feb 9                    early development in fruit flies: A-P axis                chapter 9[263-278]                                                                  

Feb 11                  early development in amphibians: overview           chapter 10

 

Feb 13                  role of induction and diffusible signals                          “     

 

Feb 16                  early development in birds                                     chapter 11

 

Feb 18                  early development in mammals                                     “                                  

 

Feb 20                  EXAM   I                                                                     -------

 

Feb 23                  neural tube formation and induction                              chapters 12 & 6

                  

Feb 25                       “        “          “          “          “                                       “       

                   

Feb 27                  differentiation of the neural tube                           chapter 12            

 

Mar 1                    development of vertebrate eye                                chapter 12

 

Mar 3                    neural crest cells and their derivatives                   chapter 13

 

Mar 5                         “         “       “     “       “          “                                    “

 

Mar 8                    nerve-target specificity                                           chapter 13

 

Mar 10                  development of somites and their derivatives         chapter 14

 

Mar 12                  development of vertebrate kidneys                                “

 

Mar 15-19            SPRING BREAK

 

Mar 22                  development of the vert heart and circulatory system  chapter 15

 

Mar 24                  development of extraembryonic membranes                       “

 

Mar 26                  development of the digestive tract in vertebrates                “

 

Mar 29                  development of the respiratory system in verts                    “

 

Mar 31                  EXAM  II                                                                       ---------

 

Apr 2                    development in flowering plants                 `           chapter 20

 

Apr 5                              “           “         “           “                                         “     

 

Apr 7                    NO CLASS--PRE-REG ADVISING

 

Apr 9                    cell differentiation                                                            chapters 3, 4 & 5         

 

Apr 12                     “           “                                                                            “         

 

Apr 14                  cell adhesion & morphogenesis                             chapter 3

                  

Apr 16                  tetrapod limb and pattern formation                      chapter 16

 

Apr 19                         “        “      “        “              “                                     “

 

Apr 21                  gonad development and sex determination                     chapter 17

 

Apr 23                  regeneration                                                           chapter 18

 

Apr 26                  metamorphosis: role of hormones in development  chapter 18

 

Apr 28                  growth and aging                                                           “

 

Apr 30                  evolutionary developmental biology                        chapter 23                                                                       

May 5                   EXAM  III                                                                   ---------

 

 

DEVELOPMENTAL BIOLOGY LABORATORY EXERCISE SCHEDULE

 

 

 

The Lab sessions meet on Tuesdays 8:30-11:15 am in F-005

 

 

Date                                                  Topic

 

Feb 3                              Mammalian Reproductive System and Gamete Formation

 

Feb 10                            Sea Urchin Fertilization and Early Development

 

Feb 17                            Frog Cleavage and Early Development

 

Feb 24                            In Vitro Chick Embryo Development

 

Mar 2                             Effects of Teratogens on Chick Development

 

Mar 9                                 “                  “          “      “              “

 

Mar 16                           Spring Break

 

Mar 23                           Regeneration in Segmented Worms

 

Mar 30                           NO Lab Meeting (pre-reg advising)

 

Apr 6                              Corn Embryo Development and Role of Hormones

 

Apr 13                               “           “             “               “      “     “        “

 

Apr 20                            Gene Expression in Drosophila

 

Apr 27                                “            “          “         “